- Baby Stores, Holyoke - Baby Accessories & Clothes
- Bakeries, Holyoke
- Baking Supplies & Needs, Holyoke - Flavoring Extracts, Flour & More
- Bank Supplies & Equipment, Holyoke
- Banks, Holyoke
- Banners, Flags, Pennants, Decals, Posters & Signs, Holyoke
- Banquet Halls, Holyoke
- Baptist Churches, Holyoke
- Barber Shops, Holyoke
- Barbers, Holyoke
- Bars, Holyoke
- Bars & Grills, Holyoke
- Baseball & Softball Clubs, Holyoke
- Batteries Dry Cell Manufacturers, Holyoke
- Batteries Dry Cell Wholesale, Holyoke
- Battery, Holyoke - Retail Batteries Stores
- Battery Manufacturers, Holyoke
- Battery Storage, Holyoke
- Battery Stores, Holyoke
- Beauty Salons, Holyoke
- Bedding & Linens Stores, Holyoke - Bed Sheets, Quilts and Coverlets, Cushions, Pillows, Slipcovers & Bed & Table Linens
- Bedroom Furniture Stores, Holyoke - Master & Kids Bedroom Furniture Sets & Beds
- Beer & Wine Stores, Holyoke
- Beer Taverns, Holyoke
- Behavioral Health Doctors, Physicians & Surgeons, Holyoke - Behavioral Medicine
- Beverage Stores, Holyoke
- Bicycle Rentals, Holyoke - Bike Rental
- Bicycle Repair & Service, Holyoke - Bike Repair Shops
- Bicycle Shops, Holyoke - Road, Hybrid, Folding, BMX, Electric & Mountain Bikes Stores & Dealers
- Big & Tall Men's Clothing, Holyoke
- Billiard & Pool Parlors, Holyoke
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- Birth Control & Family Planning Clinics, Holyoke
- Blind Organizations, Holyoke
- Boat Services, Holyoke
- Bonds, Holyoke
- Book Stores, Holyoke
- Bookkeeping Services Licensed, Holyoke
- Bookkeeping Systems & Services, Holyoke
- Books, Magazines & Newspapers Stores, Holyoke - Bookstores
- Boutiques & Boutique Items, Holyoke
- Bowling Centers, Holyoke
- Brake Lining Manufacturers, Holyoke
- Brake Service & Repair, Holyoke - Brake Pads
- Breakfast Restaurants, Holyoke
- Brick Masonry & Bricklayer Contractors, Holyoke - Brick Mason - Install & Repair
- Builders & Contractors, Holyoke
- Builders & Contractors - More, Holyoke
- Building & Home Inspection, Holyoke - Real Estate, Building, Land & House Inspection Service
- Building Cleaning - Exterior, Holyoke - Cleaning Service
- Building Construction Consultants, Holyoke - Construction Management & Consulting
- Building Hardware & Materials, Holyoke
- Building Materials & Supplies, Holyoke
- Bus Lines, Holyoke - Bus Transportation
- Bus Rental & Charter Bus Service, Holyoke
- Business & Professional Associations, Holyoke
- Business & Trade Organizations, Holyoke
- Business Brokers, Holyoke
- Business Forms, Systems & Supplies, Holyoke
- Business Legal Services, Holyoke
- Business Management Consultants, Holyoke
- Business Services, Holyoke
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