- Tailors Supplies, Southborough
- Tattooing, Southborough
- Tax Return Preparation, Southborough
- Teeth Whitening Products, Southborough
- Teeth Whitening Products & Services, Southborough
- Telecommunications, Southborough
- Telecommunications Companies, Businesses & Services, Southborough
- Temp Agencies, Southborough
- Temperature Controlled Containers, Southborough
- Temporary & Contractor Agencies, Southborough
- Testing Laboratories, Southborough - Lab Tests
- Textiles & Textile Finishing, Southborough
- Thrift Stores, Resale & Consignment Shops, Southborough
- Tile Supplies, Southborough - Tile Stores - Companies
- Tires - Wholesale & Retail, Southborough
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- Tours & Guide Services, Southborough
- Tower & Power Line Contractors, Southborough
- Towers Communications, Southborough
- Towing Service, Southborough
- Toy Stores, Southborough
- Trailer Rental & Leasing, Southborough
- Transmission Repair & Service, Southborough
- Transplant Services, Southborough
- Transportation, Southborough
- Transportation Equipment Manufacturers, Southborough
- Transportation Rental & Leasing, Southborough
- Travel & Tourism, Southborough
- Truck Repair & Service, Southborough
- Trucking - Garbage, Refuse, Waste, Trash, Scrap & Junk Removal, Southborough - Collection, Removal, Disposal, Recycling, etc
- Trust Companies, Southborough
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