- Sand Gravel & Aggregate, Florence
- Sandwich Shop Restaurants, Florence
- Savings & Loan Associations, Florence
- Savings Banks, Florence
- Seafood Restaurants, Florence
- Secondary Schools, Florence
- Secretarial & Court Reporting Services, Florence
- Security Brokers & Dealers, Florence
- Self Defense Programs, Florence
- Senior Citizens Service & Health Organizations, Florence
- Service Station Equipment - Installation, Repair & Maintenance, Florence
- Sharpening Service, Florence
- Sheet Metal, Florence
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- Sheet Metal Work - Aluminum, Tin, Stainless Steel, etc, Florence - Sheet Metal Products
- Shooting & Target Ranges, Florence
- Shopping & Shopping Services, Florence
- Siding Contractors, Florence - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Snacks & Desserts, Florence
- Social Services & Welfare, Florence
- Social Workers & Services, Florence
- Societies & Foundation Associations, Florence
- Special Interest Schools Or Instruction, Florence
- Specialty Stores, Florence
- Sporting Goods Stores, Florence
- State Government, Florence
- Stocks & Bond Brokers, Florence
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