- Sales & Order Books, Mashpee
- Sandwich Shop Restaurants, Mashpee
- Scientology Churches, Mashpee
- Scottish & Irish Goods & Products Stores, Mashpee
- Screen Houses, Mashpee
- Screen Printing, Mashpee
- Seafood Restaurants, Mashpee
- Secondary Schools, Mashpee
- Security & Surveillance System & Equipment, Mashpee
- Security Brokers & Dealers, Mashpee
- Security Guard & Patrol Service, Mashpee - Bodyguard, Guard Dogs, Etc
- Security Services, Mashpee
- Self Defense Programs, Mashpee
- Senior Citizens Service & Health Organizations, Mashpee
- Septic Tank Pumping & Cleaning, Mashpee - Septic Systems
- Sewer & Drain Cleaning & Repair, Mashpee - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Mashpee
- Sewing Machine Repair & Service, Mashpee
- Sewing Machines, Equipment & Supplies, Mashpee
- Shoe Store - More, Mashpee
- Shoe Stores, Mashpee - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Mashpee
- Shutters - Interior & Exterior, Mashpee - Wood, Vinyl, Window, Plantation Shutters, etc
- Siding Contractors, Mashpee - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, Mashpee
- Skylights, Mashpee - Skylight Shades, Blinds, Covers & More
- Small Appliances, Mashpee
- Snacks & Desserts, Mashpee
- Snow Removal Services, Mashpee - Snow Plow Service
- Social Services & Welfare, Mashpee
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- Social Workers & Services, Mashpee
- Societies & Foundation Associations, Mashpee
- Solariums & Garden Rooms, Mashpee
- Special Interest Schools Or Instruction, Mashpee
- Special Needs Transportation, Mashpee
- Specialty Animal Services, Mashpee
- Specialty Stores, Mashpee
- Speech & Hearing Specialists, Mashpee
- Speech & Language Therapy, Mashpee
- Sporting & Recreational Camps, Mashpee
- Sporting Goods Stores, Mashpee
- Sports & Recreational Services, Mashpee
- Sports Bars & Lounges, Mashpee
- Sports Medicine, Mashpee - Doctors, Physicians & Surgeons
- Sportswear Clothing Stores, Mashpee - Sports Clothes
- Spray Painting & Finishing, Mashpee - Plastic, Furniture, Acrylic, Wood & Metal
- Sprinkler System Contractors, Mashpee - Garden & Lawn Sprinkler System Installation & Repair
- Stamp Collecting & Coin Dealers , Mashpee
- Stationery & Office Supplies, Mashpee
- Steamship Companies & Agencies, Mashpee
- Steel Manufacturers, Mashpee
- Stock & Bond Brokers & Dealers, Mashpee
- Stocks & Bond Brokers, Mashpee
- Substance Abuse Clinics, Mashpee - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surveyor Services, Mashpee - Surveying Service
- Sushi Restaurants, Mashpee
- Swimming Pool, Sauna & Spa Contractors, Mashpee
- Swimming Pools Contractors, Mashpee - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Mashpee
- Swimwear & Accessories Shops, Mashpee - Water Sports Equipment
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