- Obstetricians & Gynecologists, Lowell - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Physicians & Surgeons, Lowell - Occupational Medicine
- Occupational Health Care Professionals, Lowell
- Occupational Medicine Doctors, Lowell - Physicians & Surgeons
- Office Supplies, Equipment & Office Furniture Stores, Lowell
- Oil & Gas Companies, Lowell
- Oil Burners Services, Lowell
- Oil Change & Lubrication, Lowell - Auto Oil & Quick Lube
- Oil Well Equipment & Supplies, Lowell
- Old Age Homes Service, Lowell
- Ophthalmologists, Lowell - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Goods Manufacturers, Lowell
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Lowell
- Opticians, Lowell
- Optometrists, Lowell - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Lowell - Dentists - Oral & Maxillofacial Surgeons
- Organizing Services & Products – Household & Business, Lowell
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- Organs Tuning & Repair, Lowell
- Ornamental Greenhouses, Lowell
- Ornamental Nursery, Lowell
- Ornamental Nursery Services, Lowell
- Orthodontist, Lowell - Teeth Straightening, Invisalign & Dental Braces
- Orthodox Churches, Lowell
- Orthopedic Shoes, Lowell
- Orthopedists, Lowell - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Attorneys & Lawyers, Lowell
- Other Attorneys & Lawyers, Lowell
- Other Building Materials & Supplies, Lowell
- Other Lawyers & Attorneys, Lowell
- Outdoor & Lawn & Garden Equipment Repair & Service, Lowell
- Outdoor Equipment & Accessories, Lowell
- Outpatient Clinics, Lowell - Care & Treatment Centers
- Outpatient Services, Lowell - Outpatient Care
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